Monday, September 9, 2013

Genetic Association with Primary Sjogren's Syndrome and Chronic Fatigue?

The concept of this study is intriguing:

A possible genetic association with chronic fatigue in primary Sjögren's syndrome: a candidate gene study.

Norheim KB, et al.
Journal Rheumatol Int. 2013 Sep 3. [Epub ahead of print]


Fatigue is prevalent and disabling in primary Sjögren's syndrome (pSS).......This candidate gene study in pSS did reveal a trend for associations between genetic variation in candidate genes and fatigue. The results will need to be replicated. More research on genetic associations with fatigue is warranted, and future trials should include larger cohorts and multicentre collaborations with sharing of genetic material to increase the statistical power. Continue reading here.

Interesting. Examining fatigue at a genetic level. I especially appreciate the opening statement of this abstract.

Go get 'em, guys. Research rocks.


Heda said...

Ss definitely runs in my family - grandmother, father, both aunts, sister, both first cousins, nieces. Some worse than others but all of us have symptoms - neuropathies more than fatigue but hey any Ss research is good research.

Unknown said...

Fatigue is probably the most annoying symptom I have. Because it doesn't have an outward, visible aspect that people can see, they don't believe that I am truly this tired. Then I start to doubt myself, and think I must be extremely lazy. Studies like this do so much to relived my guilt! I feel like passing them out like flyers, LOL!!