Ever play Sheepshead? According to the rules of the game followed by our family, the queen of clubs is all-powerful. She's the trump that trumps all trump. If that makes sense....
Thanks to the Sjogren's Society of Canada for tweeting the link to the results of this small study entitled Primary Sjögren's syndrome: fatigue is an ever-present, fluctuating, and uncontrollable lack of energy by Mengshoel AM1, Norheim KB, Omdal R, conducted at the University of Oslo, Oslo, Norway, and published in Arthritis Care Res 2014 Aug;66(8):1227-32. doi: 10.1002/acr.22263.
The study authors conclude:
CONCLUSION:I would agree with this study's conclusion (what an understatement), and I wish I had access to the entire study results rather than just the abstract. We need more and larger studies that examine the fatigue associated with Sjogren's syndrome. This fatigue is real, it is life-changing, and it is debilitating.
Fatigue in primary SS clearly differs from ordinary tiredness. Patients describe it as an ever-present, fluctuating, and nonrelievable lack of vitality being beyond one's own control.
I've said it before and I'll say it again: Fatigue is the _most_ catastrophic symptom of this disease for me. Yes, I have dry eyes, and yes, I have a dry mouth and enlarged parotids. I also deal with peripheral neurophathy and have a seriously cranky GI system which is in all probability related to my autoimmune disease. These things impact my life, yes.
Ah -- there's the trump card. The big one. The queen of clubs. The factor that is responsible for dictating the events of my entire life.
C'mon, research world. Get ON it. I really want to win this game.